论著
吸入七氟醚与静脉注射丙泊酚应用于小儿短小手术麻醉诱导的比较
孟庆贤
【摘要】 目的 比较吸入七氟醚和静脉注射丙泊酚在小儿短小手术麻醉诱导中的临床应用价值。方法 50 例行择期短小手术的患儿,随机均分为丙泊酚静脉麻醉诱导组(丙泊酚组)和七氟醚吸入诱导组(七氟醚组)。记录患者睫毛反射消失时间、疼痛反射消失时间、气管插管时间,监测诱导前(T0)、气管插管前(T1)、气管插管后即刻(T2)、插管后1、3、5min(T3~T5),SBP、DBP、HR、SpO2 的变化及诱导中的不良反应。
【关键字】 七氟醚,丙泊酚,麻醉诱导
中图分类号:R614文献标识码:B文章编号:1671-8194(2011)05-0020-03
[Abstract] Objective To compare clinical values of induction anesthesia with sevofi urance inhalatio and intravenous propofol in short period and small surgery for young child. Methods 50 cases received the selective operation were divided into the sevofi urance group and propofol group with 25 cases in
each group. The time to lash refl ex lost, nociceptive refl ex lost, tracheal intubation and adverse events were recorded. The SBP, DBP, HR and SpO2 were recorded before induction of anesthesia (T0), before trachea cannula (T2), the monment of trachea cannula (T3) and in 1min, 3min and 5min after cannala
(T3~T5).
七氟醚是一种新型的卤族吸入麻醉药,与其他吸入麻醉药相比,具有诱导快、呼吸道刺激小、血气分配系数低(0.63),并且吸收和清除迅速,苏醒快、麻醉深度易调节、对循环抑制轻、有一定的肌松作用等优点,容易被小儿接受。丙泊酚目前已广泛用于小儿门诊检查、有创操作以及小手术的麻醉诱导。文旨在比较七氟醚和丙泊酚在小儿短小手术麻醉诱导中的临床应用价值。